1. We have two stories in Breishit where God, or some sort of Divine messenger, damages or changes a person's body: the angel striking Jacob's thigh and God excising Adam's rib.
2. In both cases, the victim is introduced as being alone.
-Adam in 2:18:
וַיֹּאמֶר יְהוָה אֱלֹהִים, לֹא-טוֹב הֱיוֹת הָאָדָם לְבַדּוֹ; אֶעֱשֶׂה-לּוֹ עֵזֶר, כְּנֶגְדּוֹ.God said, "It is not good for Adam to be alone. I shall make him a helpmate."
וַיִּוָּתֵר יַעֲקֹב, לְבַדּוֹ; וַיֵּאָבֵק אִישׁ עִמּוֹ, עַד עֲלוֹת הַשָּׁחַרJacob was left alone - and a man wrestled with him until daybreak.
יָּבֵא אֶל-הָאָדָם, לִרְאוֹת מַה-יִּקְרָא-לוֹ; וְכֹל אֲשֶׁר יִקְרָא-לוֹ הָאָדָם נֶפֶשׁ חַיָּה, הוּא שְׁמוֹ.לְזֹאת יִקָּרֵא אִשָּׁה, כִּי מֵאִישׁ לֻקְחָה-זֹּאתGod brought all the animals to Adam, to see what he would name them, and that which Adam named the animals, that became its name . . . [regarding Eve] "This I shall name Woman, for of Man it was taken." (I've also translated q.r.a as "named" in this context - which is what it means in context, though it does weaken the point a bit.)
וַיֹּאמֶר אֵלָיו, מַה-שְּׁמֶךָ; וַיֹּאמֶר, יַעֲקֹבוַיֹּאמֶר, לֹא יַעֲקֹב יֵאָמֵר עוֹד שִׁמְךָ--כִּי, אִם-יִשְׂרָאֵל:-וַיִּשְׁאַל יַעֲקֹב, וַיֹּאמֶר הַגִּידָה-נָּא שְׁמֶךָ, וַיֹּאמֶר, לָמָּה זֶּה תִּשְׁאַל לִשְׁמִי;וַיִּקְרָא יַעֲקֹב שֵׁם הַמָּקוֹם, פְּנִיאֵלThe angel said to him, "What is you name?" He responded, "Jacob." The angel said to him, "No longer shall Jacob be said as your - rather, it shall be Israel" . . . Now Jacob asked, and said, "Please tell me your name." He responded, "Why would you ask my name?" . . . Jacob named the place Peniel.
וַיִּקַּח, אַחַת מִצַּלְעֹתָיו, וַיִּסְגֹּר בָּשָׂר, תַּחְתֶּנָּהוַיִּבֶן יְהוָה אֱלֹהִים אֶת-הַצֵּלָע אֲשֶׁר-לָקַח מִן-הָאָדָם, לְאִשָּׁה;God took one of his ribs, closing the flesh under it. God constucted Woman from the rib which he took from Adam.
וְהוּא צֹלֵעַ, עַל-יְרֵכוֹAnd Jacob was limping upon his thigh.
וַיִּקַּח מִן-הַבָּא בְיָדוֹ, מִנְחָה--לְעֵשָׂו אָחִיוזִּים מָאתַיִם, וּתְיָשִׁים עֶשְׂרִים, רְחֵלִים מָאתַיִם, וְאֵילִים עֶשְׂרִיםגְּמַלִּים מֵינִיקוֹת וּבְנֵיהֶם, שְׁלֹשִׁים; פָּרוֹת אַרְבָּעִים, וּפָרִים עֲשָׂרָה, אֲתֹנֹת עֶשְׂרִים, וַעְיָרִם עֲשָׂרָהJacob took a gift for his brother Esau from that which he owned. 200 she-goats and 20 goats; 200 ewes and 20 rams; 30 suckling camels and their young; 40 cows and 10 bulls; 20 she-asses and 10 donkeys.